Human Blood Plasma Biomarker Discovery †Myassignmenthelp.Com

Question: Discuss About The Human Blood Plasma Biomarker Discovery? Answer: Introducation The process "as is" involves making maps and charts in order to know how any particular process or job is taking place. It is, however, important to note that this will only tell us what is happening in the present time and not what should have happened or is likely to happen in future. This process mapping can be done in mainly three different levels. The least is known as the Macro, which does not give a detailed picture for analysis (Calvanese et al 2013). The next is the functional activity level and this level answers who are working in a particular process and what exactly is happening in the process. There are usually five lenses in this analysis process. In the first lens, it is usually analyzed that what exactly is the purpose behind the process and what value will this process deliver to each customer. The customers are also to be properly segmented and targeted because each customer group will have different expectations (Keshishian et al 2017). The second lens is the frustration lens that is used to see why and how the customers are frustrated due to some aspects of the process. Lens 3 is The Toyota Production System that aims at reducing the time that is the amount of time wasted. It aims at making the proper utilization of time by attacking reworks, waiting, batching etc. Lens 4 tries to inspect the present costs involved in the process like labor; overhead etc This lens actually aims at giving data in order to know whether it will be justified to spend money on a process improvement. The last and the fifth lens contains the six sigma tool (Define, Measure, Analyze, Improve, and Control) and is the most important one as it helps in checking the quality of the process, prioritize the improve methods based on the data gathered. Thus, the as is process map helps the enterprises to improve at several domains based on the data collected by each lens. Reference List Calvanese, D., De Giacomo, G. and Montali, M., 2013, June. Foundations of data-aware process analysis: a database theory perspective. InProceedings of the 32nd ACM SIGMOD-SIGACT-SIGAI symposium on Principles of database systems(pp. 1-12). ACM. Keshishian, H., Burgess, M.W., Specht, H., Wallace, L., Clauser, K.R., Gillette, M.A. and Carr, S.A., 2017. Quantitative, multiplexed workflow for deep analysis of human blood plasma and biomarker discovery by mass spectrometry.Nature protocols,12(8), p.1683.

Aids Descrimnation Is Bad Essays - HIVAIDS In Australia,

Aids Descrimnation Is Bad Discrimination is a concern for people worldwide because they have had personal experience throughout their daily routines. When it comes to people with aids, many people around the world have thought about the subject many times, and have developed their state of mind towards them. Also, people have learned to live with while others ignore the problem. One problem that may not concern many is discrimination to people with aids in school. The question here is; does aids influence schools to admit pupils? Does aid influence in teacher's grading methods? A survey done by Mauricio Murguia to six college students gave us a quite description of how more or less people think and feel about students with aids: Miriam Maciel from El Paso Community College answered, ? I don't think it is right for people to judge people with deceases because what happens to one, may happen to another. I act normal when I am aware that a person that surround me has aids and I also treat that person equally?. Another three students from UTEP answered the same. Rafael Brunet a student from Kettering University in Michigan answered that he does everything in his power to avoid people with aids and that he feels uncomfortable around these people and mostly if they are homosexuals. Luis Davalos from the TEC De Monterrey in Mexico answered that he hates people with aids because the have the decease because of irresponsibility. Also Luis Davalos told us that he couldn't see a homosexual because he is filled with anger. It is hard to make others think a way in which we think is correct and this is because we all have different points of view. I myself had an experience, which I think I will never forget. I was dating a girl about 15 months ago, and it was a normal relationship but after some time of seeing this girl I started to point out certain changes in her behavior. I thought it was because of me or because she was not happy with me so I talked to her and asked her what was wrong. She confessed to me that she had aids and that she did not know what to do. I was surprised with her confession but I could not talk for the moment. We stopped seeing each other for about two weeks. Finally I called her and asked her what she had done. She went to see a doctor and she was receiving medical assistance for her decease. I was calm and we never dated again but I still see once in a while. I call her sometimes, she calls me but we never loose contact. From my personal point of view I think that this was the best decision to take towards her and I am at peace to know that she is taken care of but I may confess that for a while I felt uncomfortable. It is hard to say how you would react towards someone if you encountered a person with the aids virus. You would have to live it to know, but it is important to be well informed with what is going on to be ready to make immediate decisions. How would you act? Medicine Essays

artist throughout history that essays

artist throughout history that essays Artists throughout History That Have Self-Destructed The most successful or famous artists are not always as happy as successful people are portrayed- living a life of fame, fortune, and glamour. The following examples will show some of the problems that four different artists have suffered in the past century.Vincent van Gogh was a Dutch painter who lived from March 30, 1853 to July 29, 1890. He is now one of the most famous painters in modern art (World Book 306). He only sold one painting in his living days, but now his paintings are considered priceless.Some of his paintings and drawings include: The Bedroom at Arles 1888 Self-Portrait 1888 Vase with 12 Sunflowers 1888 Langlois Bridge with Women Washing 1888 (Sweetman 378)Those are just a few of his accomplishments, though he has created many, many more works of art.In 1888, artist Paul Gaugin moved into Vincent's house with him. At first everything worked out fine, but within the year, their personalities started to clash , and big problems arose. Then, on December 23, 1888, Paul Gaugin was taking a walk in the nearby public garden, when, according to his memoir "Avant et Apres," Vincent chased after Gaugin with an open razor blade. But, when Gaugin turned around, Vincent turned and ran home. Gaugin decided that this threat was too much for him to take, so he checked into a hotel room for the night. When Paul Gaugin arrived at home the next morning, he saw a crowd of police officers and citizens surrounding the house. When he went in the house he saw that there was blood everywhere- on towels and blankets, then a trail leading up the stairs. When he got to Vincent's bedroom, he found him curled up on his bed covered in sheets pink with blood. Gaugin thought Vincent was dead, but when he went to touch his friend's hand, it radiat! ed warmth from his friend's body (Sweetman 290). Gaugin found out later that Vincent had cut off almost his whole left ear, wrapped it in newspape...

Answer the question Essay Example | Topics and Well Written Essays - 250 words - 3

Answer the question - Essay Example s who represented philosophers such as Aristotle and Plato produced perfect harmony to his paintings, which was an important aspect for ancient artists. The painting is asymmetrical with the main focal point being Aristotle and Plato who are the only two people standing at the front of hall with sky adjoining them as well as being centered in the hub of the composition. There is good tone in the painting with the light raying through the window creating obscurity on the ceiling of the domes giving it a three dimensional effect. The primary and secondary colors match perfectly each object and figure. Renaissance was about an artist expressing social views using paintings that could represent scholars and politicians conveying their different views. Renaissance presented a man, his visual world as well as his environment, which created the passion for skill and knowledge for the same (Rapelli 107). The painting has details on the shading and tones which highlight different Greek philosophers explaining their different beliefs and theories to each other making it a very triumphant piece of

Stem Cell Research Legislation Paper Example | Topics and Well Written Essays - 1500 words - 2

Stem Cell Legislation - Research Paper Example This paper shall discuss the history of stem cell research legislation in the United States. It shall discuss how such history compares with similar statutes around the world. The current legislative state of affairs shall also be considered, as well as the possible direction of the laws in the United States should be taken. Various studies and literature shall be considered to establish a clear and comprehensive understanding of the subject matter. Discussion What is the history of Stem Cell Research Legislation in the United States? According to Deem (2004), stem cell research on humans was first seen in the 1960s, with some success achieved in the treatment of a patient with severe combined immunodeficiency disorder. Following this success, efforts to achieve a similar success was attempted in the treatment of immunodeficiency disorders and different types of leukemia and blood disorders (Deem, 2004). Based on the success achieved for the abovementioned diseases, many people have expressed their support for the necessity of stem cell research. ... He claimed that carrying out such type of research is a threat to the unborn human life, and the government must therefore not support such procedures. The 109th and 110th Congress implemented bills which were set to overturn Bush’s position, however Bush vetoed both bills (Science Progress, 2009). In the 109th Congress, both houses approved the bill (subsequently signed by Bush) which prevented the creation of human fetuses which had the sole purpose of destroying them, as well as harvesting their body parts (Cord Bankings, 2010). A bill was also passed in order to support research into the creation of stem cell lines without damaging embryos (CBS, 2009). In 2005, the US Congress set forth the passage of the Stem Cell Research and Therapeutic Act of 2005. This was a national law which established new public banking and research facilities; this law was also set to encourage medical practitioners in increasing awareness of cord blood donations to pregnant women (Cord Blood Ban king, 2010). President Barack Obama in 2009, ended the ban on allowing federal taxpayer dollars to fund significantly broader research on embryonic stem cells. Obama’s decision provides support for research on healthier and better ways to create treatment for diseases (CBS, 2009). How does it compare to comparable statutes in the rest of the world? The controversy regarding the passage of stem cell laws around the world are more or less similar various territories. Most of these laws and countries with stem cell research laws seem to agree on the significant difference that the research can bring to various sick individuals. In Africa, there are few laws which regulate embryonic stem cell research and the only country which actually has a significant research

Working with Allied Health Professionals

Working with Allied Health Professionals This work is a reflective piece based on my experience of working within a multi-professional group setting. I will be using the model by Gibbs model (1988) to aid my reflection and present my account. Although I will be contemplating how the group performed as a whole, ultimately I aim to guide my own learning, thus aiding my preparation for future similar situations. Task Description Once strategically placed within an inter-professional group of students, we were asked to work as a team to develop an IPL strategy for the pre-registration training of Allied Health Professionals. Our efforts were to be centred on creating a twenty minute presentation based on our idea to our AHP peers. This was carried out over a week, with our presentation was expected to be given on Friday afternoon. Our Implementation of the Task and Personal Thoughts We first assembled and became acquainted with each other on Monday morning. Initial introductions and group communication were aided by a simple but effective exercise to assist preliminary group collaboration. This activity was fun, and valuable in helping us begin to establish the group relationship, and personally extinguished any uncomfortable feelings which I may usually have in a situation like this. I also felt confident that this particular group of individuals worked well together and at this point I had no concerns about the task ahead. Subsequently, we were given our main task. Although I felt that there were some very valid and intelligent thoughts brought forward during our brainstorming, I began to worry that there were perhaps too many which differed somewhat, and that as a group we were not using our time efficiently. In addition, people could not agree on the simplest practicalities, which I felt was unhelpful. The group met again on Wednesday morning, with each individual bringing their contribution of research to share. We discussed a possible structure to the presentation, although as the meeting went on it became clear that there were unquestionably some conflicting views on what our approach should be. At this point, I began to feel doubtful that the group was capable of decision-making, and started to feel anxious about our assignment. In addition, I felt that one particular member of the group seemed to feel strongly about their own outlook on the task, and that perhaps they were slightly negative regarding other ideas, unhelpful for the overall morale of the group. The following day we met in a skills lab to take some photographs for our presentation, which was successful. This was followed by a short discussion, where some of the members of the group voiced their concerns that they had lost track of how the group would present. It was then disclosed that one particular idea had been developed outside of the meetings and that there was no need to be concerned, which made me feel excluded from the decision-making. As a result, I resolved to prevent my thoughts becoming too negative by concentrating on my particular research and presentation role, accepting the decision made. On the day of the presentation, we met up beforehand and rehearsed using our amalgamated slides. I was pleasantly surprised about how the whole thing flowed, and felt relieved. The group as a whole also seemed reassured. Evaluation Individual Performance I believe that I tried my upmost to show commitment to the group and its task, and to give support when necessary. This is reflected in the peer evaluations that I received after the task was over. At the same time, I also tried to keep the group focused and remind them of time constraints. Nonetheless, I have come to realise that I was anxious and distrustful that the group would not be able to finish the work that had been set. Because of my unease of the groups relatively slow progression, I think that I subliminally withdrew from the group in that I was only confident in my own individual component of the work, deciding to stop being concerned with the overall work. One of the manners of conflict identified by John Hunt (1987) is unhelpful flight behaviour (psychological, physical or symbolic withdrawal), which blocks and inhibits group work. In my opinion this describes the negative way in which I acted, which on reflection was likely detrimental to group effectiveness. Group Performance I think our final presentation artefact was successful, reflected by the unexpectedly positive feedback which we received. I found this surprising, because of the amount of conflict and lack of decision-making that went on during the process. Charles Handy (1993) is of the opinion that although groups collaboratively produce fewer ideas than individual brainstorming, the quality of the ideas is superior in that they are more thought through and better evaluated. Even though our proposal is not what I would have gone for individually, I have come to realise that collaborative ideas are of sound quality and should not be distrusted. Despite our conflict, I realise that with regards to ethical concerns all of us were extremely understanding of certain members individual needs. For example, instances where it was necessary to consider child care issues whilst deciding meeting times were all taken into account, with everyone being very considerate and accepting. I appreciate that acting fairly and in a reasonable way to each other is critical, as agreed by the first of the four ethical principles drawn up by Beauchamp and Childress (1995): Respect for autonomy. However, in my opinion it is important to recognise that group effectiveness seemed to break down as the week went on. Aspects contributing to this included conflicting ideas, poor decision-making and lack of time for healthy group development. I firmly believe that the latter was especially damaging to our group communication. The groups decision-making was so meagre that individual members of the group had no choice but to take initiative and make decisions without the entire groups permission. Although I felt that this represented group decision-making failure, in hindsight it probably saved us from ultimate failure of the task. Analysis and Reflection of my own and my groups performance Within this section are a few key elements that I regard as being important aspects of this experience to learn from: Team-working In my opinion, there were some very good aspects within our team-working, taking into account our ultimate success. Spears (1992) describes the METHODS model, which uses an acronym for its seven concepts. I have thought about this with regards to my group experience, and feel that the team worked well in carrying out individual research, then coming together to educate each other to provide the necessary sustenance to produce the presentation. In addition, I think the team came up with exciting although challenging ideas that took the theme a creative step further, when a more demure approach would have been acceptable. Hence in my opinion, we achieved the Dream element of the model, taking the time to be imaginative. However, I think more effective team-working would have been possible if we had set clear goals to be met in our meetings, which would have avoided anxiousness and confusion. In addition, I think we would have benefitted from some outside feedback to improve our working and reduce conflicts. Furthermore, although many creative ideas were put forward, some were unfortunately met by some negative attitude damaging to the innovative environment. On reflection, I think that our group would have undoubtedly benefitted by planning our work using the METHODS model. In particular, I will definitely strongly advise my future groups to use goal-setting to encourage improvement, to gain feedback throughout and to optimise team success by encouraging innovation rather than cynicism. Decision-making I think that the groups decision-making was poor due to a combination of the large number of ideas, avoidance of conflict, and lack of planning and organisation. Although in my opinion lots of ideas can only be positive, group meetings lacking structure and orientation meant that this large amount of suggestions made things confusing, hence positive decisions were impossible to achieve. As observed by C. Handy (1999 p.173), the decision-making procedure could be by authority, majority, consensus, minority or no response. During our group work, the only decisions made were negative, via a minority or no response process. I think that this is because we failed to decide upon an appointed decision-making method during the early stages of group development. In my opinion, the role that I played within my group experience affected the decision-making negatively, in that I was so concerned the task would not be completed, I avoided conflict and went along with the strongest voice in the group. Looking back, my thinking was to try to aid progression, as I thought that further conflict would slow things down further. Works by Hall (1971) includes advice for good decision-making, for example the recommendation that group members should avoid changing their minds merely to avoid conflict, and to actively seek out differences of opinion. This is something I will take with me and implement in future situations. From this reflection, I have learnt that forward planning is key. For example, an authoritative leader should be appointed from the beginning, as should a method of decision-making. In addition, meetings should be planned and well structured, with goals set to be met by the end of each one. Diversity and Difference Current theory by Cox (1993) states that although diversity in groups often leads to disagreements, it also means more productivity than with a group which is more homogenous, including a higher level of creativity and innovation. In my group experience, there was some definite heterogeneity within group members characteristics, including different personalities, attitudes, and in turn influence and group integration. I think that this was the cause of the conflict that occurred, although as I have already mentioned, the group did collaboratively produce a vast range of ideas and importantly was successful in its end goal. I believe that although conflict would have been absent had there been less diversity, so would have the quantity and quality of imaginative ideas. To reflect upon my group role, I will use Holm and Stevensons prompt questions (1994): What was my role in this situation and was I comfortable? Belbin (1981) noted that if any of the eight team roles is absent or inadequate, the overall team will be off-balance. Prior to meeting my group, I carried out a Belbins Team Roles Questionnaire, finding that typically I am an Implementer and Teamworker. In retrospect, whilst I was part of this particular group, I believe that I took on a different role. Although I remained an Implementer, in my opinion I acted more as a Completer-finisher than a Teamworker, considering my anxiousness that the group was inefficient and that the task may not get done on time. I believe my role changed to facilitate the groups progression and even out an imbalance. This change did cause me to feel slightly uncomfortable, mainly due to the unease associated with it. How did others act? Were the actions appropriate? Looking back, I think that in particular there were too many team workers. The group regarded the conflict and tension that had occurred as negative, and people were keen to avoid this as much as possible. Although our actions were appropriate given our situation and the task at hand, things may have been implemented in a more effective and planned way. From this reflection, I have come to realise that some diversity (although associated with disagreement) is positive, and ultimately necessary for good productivity. Additionally, although each team role is associated with some negative aspects, all are crucial for good team-working. I will bear all this in mind in future, and will no longer shy away from some healthy conflict. Management of power and conflict When the group met after each individuals research, there was some tension and disagreement over the groups priorities, and the method by which the task should be carried out. As conflict continued pressure mounted, not helped by time constraints of the room booking. The Tuckman stages of group development (1965) describe part of the Storming stage as the group beginning to settle disagreements and setting priorities, however this was unachievable due to lack of time available. As a result of this situation a clear leader surfaced, providing much needed structure and clarity. She listened to everything that all had to say, somehow having the ability to create an innovative environment whilst simultaneously bringing some degree of organisation into the proceedings, precisely what the group was actively looking for. She also had huge confidence in the group as a whole, emitting positivity and confidence, vital to the needs of the team at the time. Although the storming stage was not entirely complete, the norming stage commenced because of this newly-found structure. Even so, as I have described disagreements were not all entirely resolved. This resulted in tension and some continuing conflict being present within the group throughout the rest of our time together. This was unfortunate, as one particular member of the group began to interpret some of the discussion as being a personal attack, thus becoming defensive. However, I am pleased to say that on the day of the presentation we managed to set aside all hostility and presented our work proudly together and as a team. From this analysis element, I have come to realise that time should be made for healthy group development to allow time for conflict resolution. Clinical Reasoning One of the CAIPE principles of effective Interprofessional Education (2002) is to respect the contribution of each professional within the patient care pathway. As a group, I think we demonstrated this, as there was much amicability in considering each others needs, responsibilities and alternative responsibilities in order to reason meeting times and the amount and type of individual work each person took on. It was reassuring to realise that this is possible within interprofessionals. One of the thoughts behind interprofessional learning is that it enables professionals to learn with, from and about each other to improve collaboration and the quality of care. In terms of my own personal experience of the group work I think I have certainly significantly enhanced my knowledge of other healthcare professionals alongside the undertaking of the task. This module has allowed me to further appreciate the value of the IPL activities that are in place as part of our learning, for example the observation of MDT meetings. I appreciate that my learning would benefit from developing my clinical reasoning skill set further, and I have identified this as an essential area for my professional development. Conclusion The conclusion is a fundamental part of the Gibbs model of reflection, prompting reflection on what else I could have done. To aid this, I shall continue to refer to a selection of Holm and Stevensons reflection questions: How could I have improved the situation? By easing my anxiety in having more trust in my peers and in the group as a whole, my personal experience would have been much more positive. In addition, forward planning, for example the setting of goals and early decisions as to how the group will work would have been beneficial. Do I feel as if I have learnt anything new about myself? I have become aware that I am able to be flexible according to the needs of my group in the role that is required of me. I see this as a positive concept, as during my time as a healthcare practitioner, I will come across a diverse range of situations, where malleability will be key. Has it changed my way of thinking in any way? I have come to realise that individuals are diverse in their characteristics, attitudes and beliefs, and appreciate that this diversity is very positive within a group setting. I have also come to realise that a degree of conflict is good for productivity and creativity (although time must be allocated for any conflict to be resolved). Action Plan Attend a successful team worker course to work on my group skills. Find ways of relieving anxiety, by perhaps attending a course on this. Strongly suggest use of the METHODS model during future group scenarios to aid effective team-working. Strongly propose to decide on a decision-making procedure early on in a future group situation. Actively make time for healthy group development. Ask for relevant and professional feedback to be given to the group throughout. Try out different reflection models for different experiences to help me determine which are most useful for my own personal learning and to aid me in becoming a successful reflective practitioner. Participate in as many IPL activities as possible to develop my clinical reasoning skills.

The Symbol of Blood in William Shakespeares Macbeth Essay -- William

The Symbol of Blood in William Shakespeare's Macbeth Blood represents life, death and often injury. It is an essential part of life, and without blood, we could not live. In Macbeth, Shakespeare uses the symbol of blood to represent treachery, murder and death. The word "blood", or different forms of it, appear numerous times throughout the play. Interestingly, the symbol of blood changes throughout the play, corresponding to the atmosphere and mood changes in the characters and the play. First, blood is a reference of honor, and this occurs when Duncan sees the injured sergeant and says, "What bloody man is that?"(1.2.1). This is symbolic of the brave fighter who been injured in a valiant battle for Scotland. The sergeant goes on to describe the courageous actions of Macbeth and says, "With his brandished steel, which smoked with bloody execution . . . [Macbeth] unseamed [Macdonwald] from the nave to th? chops"(1.2.20&23). This refers to Macbeth?s braveness in confronting and executing Macdonwald in battle, using his sword that is covered in the blood of the enemy. ...